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Delamanid [Dlm] Drug Dosages and Duration
Delamanid (Dlm) is used for longer oral MDR/XDR-TB regimens. It is available as 50mg tablets, administered for 24 weeks. Dosage varies by age: 100mg BID for adults/adolescents, 50mg BID for children 6-11 years.
Published on November 5, 2025
Delamanid (Dlm) Drug Dosages and Duration
Delamanid (Dlm) is considered only for the longer oral Multi (M)/ Extensively Drug-resistant TB (XDR-TB) regimen as per the Programmatic Management of Drug-resistant TB (PMDT) guidelines.
Formulation:
Film-coated tablet with 50 mg Delamanid
Duration:
24 weeks. The Optimal Background Regimen (OBR) will be continued beyond the 24 weeks of Dlm administration.
Dosage:
- Adolescent (12-17 years) and adults: 100 mg orally twice daily (two tablets of 50 mg)
- Children (6-11 years): 50 mg orally twice daily
Resources:
- Guidelines for Programmatic Management of Drug-resistant Tuberculosis in India, March 2021
- World Health Organization. The use of Delamanid in Treatment of Multidrug-resistant Tuberculosis: Interim Policy Guidance, 2016
- Guidelines for the Use of Delamanid in the Treatment of Drug-resistant TB in India, 2018
- Consolidated Guidelines on Tuberculosis, Module 4- Treatment: Drug-resistant TB Treatment